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Symbol
Name
ID 		Tardbp
TAR DNA binding protein
MGI:2387629
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Female sexual dysfunction
Male sexual dysfunction
Disease(s) Associated with TARDBP
Parkinson's disease

Mouse Phenotypes
abnormal sperm flagellum morphology
oligozoospermia
teratozoospermia
abnormal sperm head morphology
absent sperm head
decreased male germ cell number
increased male germ cell apoptosis
abnormal seminiferous tubule epithelium morphology
small seminiferous tubules
seminiferous tubule degeneration
decreased testis weight
small testis
abnormal chromosomal synapsis
arrest of male meiosis
arrest of spermatogenesis
reduced male fertility
Availability Mouse Genotype
Tardbptm1.1Pcw/Tardbptm1.1Pcw
Tg(Stra8-icre)1Reb/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory